The treatment of gout aims to relieve pain and inflammation during acute attacks, prevent future attacks and lower uric acid levels in the blood to prevent the formation of urate crystals in the joints.

Standard urate-lowering medicines are:

• Allopurinol

  This is an oral prescription that helps lower serum uric acid levels.

• Febuxostat

  This is another urate-lowering therapy. This medication is taken orally and decreases the body’s production of uric acid. It can be taken by people with mild to moderate kidney or liver disease.

Colchicine add-on to allopurinol drastically reduces flare recurrence, when initiating a gout prevention therapy

Borstad GC et al. demonstrated that colchicine
0.6 mg reduced the frequency of gout flares¹¹

When initiating therapy to lower urate levels, 75% of the patients will experience one to several new  gout flares within first 6 months¹³.

When preventing recurrent gout flares colchicine in low dose can significantly reduce the number of flares when given in combination with uricosuric drugs¹².

42 patients starting allopurinol were randomized to receive colchicine 0.6 mg or placebo for up to 6 months. The chart shows mean number of acute gout flares at the 0-3 and 3-6 month time periods, and overall (n=43; colchicine=21, placebo=22)